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\"\"<\/figure>
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MECC\u306e\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u90e8\u9580\u306b\u6240\u5c5e\u3057\u30662\u5e74\u76ee\u306e\u7814\u7a76\u54e1\u3002
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\u7279\u6280\uff1a\u4e2d\u56fd\u8a9e<\/p>\n\n\n\n

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PDT\u306f\u3001\u5149\u5897\u611f\u5264\u3068\u547c\u3070\u308c\u308b\u5149\u6d3b\u6027\u5206\u5b50(PS)\u3092\u6295\u4e0e\u3057\u3066\u304c\u3093\u7d30\u80de\u306b\u5438\u53ce\u3055\u305b\u3001\u6a19\u7684\u90e8\u4f4d\u306b\u7279\u5b9a\u306e\u6ce2\u9577\u3092\u7167\u5c04\u3059\u308b\u3053\u3068\u3067PS\u304c\u6d3b\u6027\u5316\u3055\u308c\u3066\u3001\u767a\u751f\u3057\u305f\u4e00\u91cd\u9805\u9178\u7d20\u306b\u3088\u308a\u69d8\u3005\u306a\u751f\u4f53\u5206\u5b50\u304c\u9178\u5316\u3055\u308c\u6a19\u7684\u7d44\u7e54\u304c\u4e0d\u53ef\u9006\u7684\u306b\u7834\u58ca\u3055\u308c\u308b\u3068\u3044\u3046\u539f\u7406\u306e\u6cbb\u7642\u6cd5\u3067\u3059\u3002<\/p>\n\n\n\n

PS\u306b\u306f\u3001\u30dd\u30eb\u30d5\u30a3\u30ea\u30f3(Por)\u3068\u305d\u306e\u8a98\u5c0e\u4f53\u304c\u3088\u304f\u5229\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002Por\u306f\u4e00\u91cd\u9805\u9178\u7d20\u91cf\u5b50\u53ce\u7387\u306e\u9ad8\u3055\u3084\u6700\u5c0f\u9650\u306e\u6697\u6240\u6bd2\u6027\u3092\u6709\u3057\u3001\u4f53\u5185\u304b\u3089\u901f\u3084\u304b\u306b\u9664\u53bb\u3055\u308c\u308b\u306a\u3069\u306e\u5229\u70b9\u304c\u3042\u308b\u4e00\u65b9\u3067\u3001\u5168\u8eab\u6295\u4e0e\u3067\u306f\u5b89\u5b9a\u3057\u305f\u52b9\u679c\u3092\u767a\u63ee\u3059\u308b\u305f\u3081\u306b\u5fc5\u8981\u306a\u6295\u4e0e\u91cf\u304c\u591a\u304f\u5149\u611f\u53d7\u6027\u306e\u9577\u671f\u5316\u306b\u3064\u306a\u304c\u308b\u3053\u3068\u3084\u3001\u816b\u760d\u5c40\u6240\u3092\u6a19\u7684\u3068\u3059\u308b\u307e\u3067\u306b\u5316\u5408\u7269\u304c\u6d88\u5931\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u306a\u3069\u3001\u3044\u304f\u3064\u304b\u306e\u6b20\u70b9\u3082\u6319\u3052\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n

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\"\"<\/figure>
\n

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\u3008\u6750\u6599\u3009<\/mark><\/strong>
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\u3008\u65b9\u6cd5\u3009<\/mark><\/strong>
Por\u3092\u5408\u6210\u3057\u3066\u4e00\u91cd\u9805\u9178\u7d20\u3068\u5149\u7dda\u529b\u5b66\u7684\u4f5c\u7528\u3092\u8a55\u4fa1\u3057\u305f\u306e\u3061\u3001\u30a8\u30ec\u30af\u30c8\u30ed\u30b9\u30d4\u30cb\u30f3\u30b0\u6280\u8853\u3092\u5229\u7528\u3057\u3066\u3001\u30b3\u30a2\u30b7\u30a7\u30eb\u30a8\u30ec\u30af\u30c8\u30ed\u30b9\u30d4\u30cb\u30f3\u30b0\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306bPor\u3092\u7d44\u307f\u8fbc\u307f\u307e\u3057\u305f\u3002\u3053\u306e\u969b\u3001\u30b3\u30a2\u5c64\u306bPVA\u3001\u30b7\u30a7\u30eb\u5c64\u306b\u306fGel\u3092\u4f7f\u7528\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u3057\u3066\u3001\u30a8\u30ec\u30af\u30c8\u30ed\u30b9\u30d4\u30cb\u30f3\u30b0\u306b\u3088\u308a\u4f5c\u88fd\u3055\u308c\u305f\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u3092\u7279\u6027\u8a55\u4fa1\u3057\u3001\u816b\u760d\u7d30\u80de\u682a\u53ca\u3073\u975e\u816b\u760d\u7d30\u80de\u682a\u306b\u5bfe\u3059\u308b\u6697\u6240\u6761\u4ef6\u4e0b\u304a\u3088\u3073\u653e\u5c04\u7dda\u7167\u5c04\u4e0b\u3067\u306e\u6bd4\u8f03\u3001\u85ac\u7269\u653e\u51fa\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

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\u3008\u7d50\u679c\u3009<\/mark><\/strong>
\u30fb\u816b\u760d\u7d30\u80de\u682a\u53ca\u3073\u975e\u816b\u760d\u7d30\u80de\u682a\u3067\u306ePor\u306e\u4e00\u91cd\u9805\u9178\u7d20\u767a\u751f\u3068\u7d30\u80de\u6bd2\u6027<\/p>\n\n\n\n

\u3059\u3067\u306b\u767a\u8868\u3055\u308c\u3066\u3044\u308b\u5b9f\u9a13\u624b\u9806\u304b\u30895,10,15,20-\u30c6\u30c8\u30e9\u30ad\u30b9\uff084-\u30ab\u30eb\u30dc\u30ad\u30b7\u30e1\u30c1\u30eb\u30c1\u30aa-2,3,5,6-\u30c6\u30c8\u30e9\u30d5\u30eb\u30aa\u30ed\u30d5\u30a7\u30cb\u30eb\uff09\u30dd\u30eb\u30d5\u30a3\u30ea\u30f3\uff08TPPF16<\/sub>[S-CH2<\/sub>-COOH]4<\/sub>\uff09\u306e\u5408\u6210\u3092\u884c\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

TPPF16<\/sub>[S-CH2<\/sub>-COOH]4<\/sub>\u306e\u4e00\u91cd\u9805\u9178\u7d20\u767a\u751f\u80fd\u306f\u3001\u30c6\u30c8\u30e9\u30d5\u30a7\u30cb\u30eb\u30dd\u30eb\u30d5\u30a3\u30ea\u30f3(TPP)\u306e\u7d50\u679c\u3068\u540c\u7a0b\u5ea6\u306e\u751f\u6210\u80fd\u3067\u3042\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3067\u304d\u305f\u305f\u3081\u3001\u4ee5\u4e0b\u306e\u5b9f\u9a13\u306b\u5229\u7528\u3057\u3066\u3044\u304d\u307e\u3059\u3002<\/p>\n\n\n\n

\u6b21\u306b\u3001\u816b\u760d\u7d30\u80de\u30fb\u975e\u816b\u760d\u7d30\u80de\u306b\u5bfe\u3059\u308b\u7d30\u80de\u6bd2\u6027\u3092\u8a55\u4fa1\u3057\u307e\u3057\u305f\u3002\u7d30\u80de\u5897\u6b96\u309250\uff05\u963b\u5bb3\u3059\u308b\u305f\u3081\u306b\u5fc5\u8981\u306aPor\u6fc3\u5ea6(GI50<\/sub>\u5024)\u3092\u898b\u308b\u3068\u3001\u6697\u6240\u6761\u4ef6\u4e0b\u3068\u6bd4\u8f03\u3059\u308b\u3068\u5149\u7167\u5c04\u4e0b\u3067\u306f\u975e\u5e38\u306b\u4f4e\u3044\u5024\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u306b\u3088\u308a\u3001\u816b\u760d\u7d30\u80de\u306e\u5897\u6b96\u3092\u963b\u5bb3\u3059\u308b\u305f\u3081\u306b\u306f\u975e\u5e38\u306b\u4f4e\u6fc3\u5ea6\u306ePor\u304c\u5fc5\u8981\u3067\u3042\u308a\u3001PS\u304c\u5149\u7167\u5c04\u4e0b\u3067\u9ad8\u3044\u7d30\u80de\u6bd2\u6027\u3092\u793a\u3057\u304c\u3093\u7d30\u80de\u306b\u5bfe\u3059\u308b\u5149\u7dda\u529b\u5b66\u7684\u52b9\u7387\u304c\u5b9f\u8a3c\u3055\u308c\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u975e\u816b\u760d\u7d30\u80de\u3067\u306eGI50<\/sub>\u5024\u304b\u3089\u6697\u6240\u6761\u4ef6\u4e0b\u3068\u5149\u7167\u5c04\u6642\u3069\u3061\u3089\u3082\u9ad8\u6fc3\u5ea6\u306ePor\u304c\u5fc5\u8981\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3001Por\u304c\u975e\u816b\u760d\u7d30\u80de\u3088\u308a\u3082\u816b\u760d\u7d30\u80de\u306b\u5bfe\u3057\u3066\u7d30\u80de\u6bd2\u6027\u304c\u9ad8\u3044\u3053\u3068\u3092\u88cf\u4ed8\u3051\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

\u3055\u3089\u306b\u3001Por\u306f\u816b\u760d\u7d30\u80de\u306b\u5bfe\u3057\u3066\u5149\u7167\u5c04\u6761\u4ef6\u4e0b\u3067\u306f\u6697\u6240\u6761\u4ef6\u306e11\u500d\u306e\u5149\u6bd2\u6027\u3092\u793a\u3057\u3001\u975e\u816b\u760d\u7d30\u80de\u3067\u306f\u308f\u305a\u304b2\u500d\u3067\u3042\u3063\u305f\u3053\u3068\u304b\u3089\u3001Por\u306e\u5149\u6bd2\u6027\u306f\u975e\u816b\u760d\u7d30\u80de\u3067\u306f\u8efd\u6e1b\u3055\u308c\u308b\u3053\u3068\u3092\u793a\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

\u30fbPVA\uff0d\u30bc\u30e9\u30c1\u30f3\u30b3\u30a2\u30b7\u30a7\u30eb\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u3078\u306ePor\u306e\u7d44\u307f\u8fbc\u307f PVA\uff0d\u30bc\u30e9\u30c1\u30f3\u30b3\u30a2\u30b7\u30a7\u30eb\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306f\u540c\u8ef8\u30a8\u30ec\u30af\u30c8\u30ed\u30b9\u30d4\u30cb\u30f3\u30b0\u6cd5\u3092\u5229\u7528\u3057\u3066\u4f5c\u88fd\u3057\u305f\u3002\u540c\u8ef8\u30a2\u30af\u30bb\u30b5\u30ea\u30fc\u306f\u753b\u50cf\u306e\u3082\u306e\u3092\u4f5c\u88fd\u3057\u305f\u3002<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

(Sofia M. Costa, Leandro M. O. Louren\u00e7o, Ricardo C. Calhelhacd, et al. : Localized cancer photodynamic therapy approach based on core\u2013shell electrospun nanofibers, Materials Advances , Issue 16, 6489-6500,21th August 2024.\u3000\u3088\u308a\u5f15\u7528)<\/p>\n\n\n\n

<\/div>\n\n\n\n
\"\"<\/figure>
\n

\u4f7f\u7528\u3055\u308c\u305f\u30b9\u30d4\u30ca\u30ec\u30c3\u30c8\u306f\u3001\u5f0a\u793e\u3067\u8ca9\u58f2\u3057\u3066\u3044\u308b\u82af\u9798\u30b9\u30d4\u30ca\u30ec\u30c3\u30c8\u3067\u3059\uff01<\/strong><\/p>\n<\/div><\/div>\n\n\n\n

<\/div>\n\n\n\n

\u4f5c\u88fd\u3057\u305f\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306fFESEM\u3001TEM\u3001TGA\u3001ATR\uff0dFTIR\u306b\u3088\u308a\u7279\u5fb4\u3065\u3051\u3089\u308c\u3001PVA\u3068\u30bc\u30e9\u30c1\u30f3\u306e\u4e21\u65b9\u306e\u30dd\u30ea\u30de\u30fc\u304c\u5b58\u5728\u3057\u3066\u3044\u3066\u3001\u8868\u9762\u304c\u6ed1\u3089\u304b\u3067\u6b20\u9665\u306e\u306a\u3044\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u3067\u3042\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3067\u304d\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

Por\u3092\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306b\u7d44\u307f\u8fbc\u3080\u969b\u306bGI50<\/sub>\u5024\u3092\u8003\u616e\u3057\u30014\u7a2e\u306ePor\u6fc3\u5ea6\u306e\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u3092\u4f5c\u88fd\u3057\u3001\u8a55\u4fa1\u30fb\u5206\u6790\u3092\u884c\u3044\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

PVA\u306bPor\u3092\u6dfb\u52a0\u3059\u308b\u3068Por\u6fc3\u5ea6\u306b\u5fdc\u3058\u3066\u6eb6\u6db2\u306e\u7c98\u5ea6\u30fb\u5c0e\u96fb\u7387\u304c\u5897\u52a0\u3057\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u3001Por\u7d44\u307f\u8fbc\u307f\u306b\u3088\u308a\u96fb\u8377\u5bc6\u5ea6\u304c\u5897\u52a0\u3057\u3001\u5c0e\u96fb\u7387\u5024\u304c\u4e0a\u6607\u3057\u653e\u51fa\u3055\u308c\u308b\u30b8\u30a7\u30c3\u30c8\u306e\u4f38\u3073\u529b\u304c\u5f37\u304f\u306a\u3063\u305f\u3053\u3068\u3067\u3001\u7e4a\u7dad\u5f84\u306e\u6e1b\u53ce\u304c\u4fc3\u9032\u3055\u308c\u3066\u3044\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n

<\/div>\n\n\n\n
\"\"<\/figure>
\n

\u7e4a\u7dad\u5f84\u306f\u5e73\u5747125nm\u3068\u304b\u306a\u308a\u7d30\u304f\u306a\u3063\u3066\u3044\u305f\u3088\u3046\u3067\u3059\u3002<\/strong><\/p>\n<\/div><\/div>\n\n\n\n

<\/div>\n\n\n\n

\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u4e2d\u306ePor\u306e\u5b58\u5728\u78ba\u8a8d\u3092GSDR\u306b\u3066\u884c\u3044\u307e\u3057\u305f\u3002PS\u306e\u7279\u5fb4\u7684\u306a\u5438\u53ce\u5e2f\u304c\u898b\u3089\u308c\u3001\u5f97\u3089\u308c\u305f\u30b9\u30da\u30af\u30c8\u30eb\u306fPor\u306e\u307f\u306e\u30b9\u30da\u30af\u30c8\u30eb\u3068\u975e\u5e38\u306b\u985e\u4f3c\u3057\u3066\u304a\u308a\u3001\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u3078\u306ePor\u306e\u5b58\u5728\u304c\u78ba\u8a8d\u3055\u308c\u3001Por\u6fc3\u5ea6\u3092\u4e0a\u3052\u308b\u3068\u30d0\u30f3\u30c9\u306e\u5f37\u5ea6\u304c\u5897\u52a0\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

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\u307e\u305f\u3001\u30a8\u30ec\u30af\u30c8\u30ed\u30b9\u30d4\u30cb\u30f3\u30b0\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306f\u3001\u9ad8\u3044\u62c5\u6301\u80fd\u3068\u9ad8\u3044\u30ab\u30d7\u30bb\u30eb\u5316\u52b9\u7387\u3092\u7279\u5fb4\u3068\u3057\u3066\u304a\u308a\u3001\u85ac\u7269\u9001\u9054\u3078\u306e\u975e\u5e38\u306b\u9b45\u529b\u7684\u306a\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002PVA\uff0d\u30bc\u30e9\u30c1\u30f3\uff0bPor\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306e\u62c5\u6301\u80fd\u3068\u30ab\u30d7\u30bb\u30eb\u5316\u52b9\u7387\u3092\u6e2c\u5b9a\u3057\u305f\u7d50\u679c\u3001\u3069\u3061\u3089\u3082\u9ad8\u3044\u5024\u3092\u793a\u3057\u3001DDS\u306b\u9069\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u5b9f\u8a3c\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

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\u30fb\u30b3\u30a2\u30b7\u30a7\u30eb\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u304b\u3089\u306ePor\u653e\u51fa\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb<\/p>\n\n\n\n

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PVA\uff0d\u30bc\u30e9\u30c1\u30f3\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u3068PVA\uff0d\u30bc\u30e9\u30c1\u30f3\uff0bPor\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u3092\u7528\u3044\u3066\u5f97\u3089\u308c\u305f\u5438\u53ce\u30b9\u30da\u30af\u30c8\u30eb\u3068\u85ac\u7269\u653e\u51fa\u30d7\u30ed\u30d5\u30a1\u30a4\u30eb\u3092\u30b0\u30e9\u30d5\u306b\u3057\u3066\u8868\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

(Sofia M. Costa, Leandro M. O. Louren\u00e7o, Ricardo C. Calhelhacd, et al. : Localized cancer photodynamic therapy approach based on core\u2013shell electrospun nanofibers, Materials Advances , Issue 16, 6489-6500,21th August 2024.\u3000\u3088\u308a\u5f15\u7528)<\/p>\n\n\n\n

<\/div>\n\n\n\n

PVA\uff0d\u30bc\u30e9\u30c1\u30f3\uff0bPor\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306e\u30b9\u30da\u30af\u30c8\u30eb\u3067\u306e\u307f\u5178\u578b\u7684\u306a\u5438\u53ce\u30d0\u30f3\u30c9\u306e\u51fa\u73fe\u304c\u307f\u3089\u308c\u3001\u6642\u9593\u306e\u7d4c\u904e\u3068\u3068\u3082\u306bPor\u304c\u653e\u51fa\u3055\u308c\u308b\u3053\u3068\u3092\u793a\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n

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<\/div>\n\n\n\n
\"\"<\/figure>\n\n\n\n

(Sofia M. Costa, Leandro M. O. Louren\u00e7o, Ricardo C. Calhelhacd, et al. : Localized cancer photodynamic therapy approach based on core\u2013shell electrospun nanofibers, Materials Advances , Issue 16, 6489-6500,21th August 2024.\u3000\u3088\u308a\u5f15\u7528)<\/p>\n\n\n\n

<\/div>\n\n\n\n

PVA\uff0d\u30bc\u30e9\u30c1\u30f3\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306f\u816b\u760d\u7d30\u80de\u306b\u5bfe\u3059\u308b\u6697\u6240\u6761\u4ef6\u4e0b\u53ca\u3073\u5149\u7167\u5c04\u4e0b\u3068\u3082\u306b\u4f4e\u3044\u963b\u5bb3\u7387\u3092\u793a\u3057\u3001\u6700\u5c0f\u9650\u306e\u7d30\u80de\u6bd2\u6027\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u4e21\u6761\u4ef6\u4e0b\u3067\u306e\u6570\u5024\u3082\u985e\u4f3c\u3057\u3066\u304a\u308a\u3001\u7167\u5c04\u4e0b\u3067\u306e\u7279\u6027\u304c\u793a\u3055\u308c\u3066\u3044\u306a\u3044\u3053\u3068\u304c\u78ba\u8a8d\u3067\u304d\u307e\u3059\u3002<\/p>\n\n\n\n

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<\/p>\n\n\n\n

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\u3053\u308c\u3089\u306e\u7e4a\u7dad\u72b6\u30ca\u30ce\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u306fPor\u306e\u9ad8\u3044\u62c5\u6301\u80fd\u3068\u9ad8\u3044\u30ab\u30d7\u30bb\u30eb\u5316\u52b9\u7387\u3092\u793a\u3057\u3001\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u304b\u3089Por\u653e\u51fa\u306f9\u65e5\u9593\u9023\u7d9a\u7684\u306b\u653e\u51fa\u3055\u308c\u307e\u3057\u305f\u3002\u521d\u671f\u6bb5\u968e\u306f\u653e\u51fa\u304c\u65e9\u304f\u3001\u305d\u306e\u5f8c\u3086\u3063\u304f\u308a\u3068\u6301\u7d9a\u7684\u306a\u653e\u51fa\u304c\u7d9a\u3044\u3066\u3044\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306e\u30b3\u30a2\u30b7\u30a7\u30eb\u69cb\u9020\u306b\u3088\u308b\u3082\u306e\u3060\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/p>\n\n\n\n

PVA\uff0d\u30bc\u30e9\u30c1\u30f3\uff0bPor\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306f\u5149\u7dda\u529b\u5b66\u7684\u52b9\u679c\u3092\u793a\u3057\u307e\u3057\u305f\u3002\u816b\u760d\u7d30\u80de\u306e\u5897\u6b96\u3092\u6291\u5236\u3059\u308b\u5272\u5408\u304c\u6697\u6240\u6761\u4ef6\u4e0b\u3088\u308a\u3082\u5149\u7167\u5c04\u4e0b\u3067\u9ad8\u304b\u3063\u305f\u3053\u3068\u304b\u3089\u3001PVA\uff0d\u30bc\u30e9\u30c1\u30f3\uff0bPor\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u304c\u653e\u5c04\u7dda\u306b\u66dd\u3055\u308c\u305f\u3068\u304d\u3001\u816b\u760d\u7d30\u80de\u306e\u5897\u6b96\u3092\u6291\u5236\u3059\u308b\u80fd\u529b\u304c\u3042\u308b\u3053\u3068\u304c\u78ba\u8a8d\u3067\u304d\u3001\u3055\u3089\u306b\u816b\u760d\u7d30\u80de\u682a\u3067\u306f\u3001\u975e\u816b\u760d\u7d30\u80de\u682a\u3068\u6bd4\u8f03\u3057\u3066\u9078\u629e\u7684\u306a\u5149\u7d30\u80de\u6bd2\u6027\u4f5c\u7528\u304c\u307f\u3089\u308c\u307e\u3057\u305f\u3002 \u672c\u7814\u7a76\u3067\u306fPS\u3092\u7d44\u307f\u8fbc\u3093\u3060\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u304c\u3001\u304c\u3093PDT\u7279\u306b\u5b50\u5bae\u9838\u304c\u3093\u306b\u5bfe\u3059\u308b\u5c40\u6240\u7684\u306aDDS\u3068\u3057\u3066\u6a5f\u80fd\u3057\u3001Por\u306e\u9023\u7d9a\u653e\u51fa\u3092\u53ef\u80fd\u306b\u3059\u308b\u5927\u304d\u306a\u53ef\u80fd\u6027\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n

<\/div>\n\n\n\n
\"\"<\/figure>
\n

\u524d\u56de\u3082\u30a8\u30ec\u30af\u30c8\u30ed\u30b9\u30d4\u30cb\u30f3\u30b0\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306b\u3088\u308bDDS\u306e\u6587\u732e\u3092\u7d39\u4ecb\u3055\u305b\u3066\u3044\u305f\u3060\u304d\u307e\u3057\u305f\u304c\u3001\u7528\u9014\u3084\u6750\u6599\u306e\u7d44\u307f\u5408\u308f\u305b\u30fb\u4f5c\u88fd\u65b9\u6cd5\u306b\u3088\u3063\u3066\u7570\u306a\u308b\u6cbb\u7642\u6cd5\u306b\u5fdc\u7528\u3067\u304d\u3001\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306e\u6c4e\u7528\u6027\u3092\u6539\u3081\u3066\u5b9f\u611f\u3057\u307e\u3057\u305f\uff01<\/strong>
\u526f\u4f5c\u7528\u306e\u5c11\u306a\u304f\u52b9\u679c\u7684\u306a\u304c\u3093\u6cbb\u7642\u306e\u305f\u3081\u306b\u30b3\u30a2\u30b7\u30a7\u30eb\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306b\u3088\u308bDDS\u306f\u3068\u3066\u3082\u52b9\u679c\u7684\u3067\u3059\u306d\u3002
\u304c\u3093\u306b\u7f79\u60a3\u3055\u308c\u308b\u65b9\u304c\u65e5\u672c\u3067\u3082\u5e74\u3005\u5897\u3048\u3066\u3044\u308b\u305f\u3081\u3001\u3053\u306e\u7814\u7a76\u304c\u3055\u3089\u306b\u9032\u3080\u3053\u3068\u3067\u7f79\u60a3\u3055\u308c\u305f\u65b9\u306e\u6cbb\u7642\u304c\u3001\u526f\u4f5c\u7528\u304c\u306a\u304f\u52b9\u679c\u7684\u306a\u3082\u306e\u306b\u306a\u308a\u305d\u3046\u3067\u3059\u306d\u263b\u4eca\u5f8c\u306e\u9032\u5c55\u306b\u671f\u5f85\u5927\u3067\u3059\uff01\uff01\uff01<\/p>\n<\/div><\/div>\n\n\n\n


\u5f0a\u793e\u3067\u306f\u3001\u69d8\u3005\u306a\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u30b5\u30f3\u30d7\u30eb<\/strong>\u3092\u4f5c\u88fd\u3057\u3066\u304a\u308a\u307e\u3059\u3002
\u8a66\u3057\u305f\u3044\u6750\u6599\u3084\u7d21\u7cf8\u306b\u95a2\u3059\u308b\u8cea\u554f\u304c\u3042\u308c\u3070\u3001\u304a\u6c17\u8efd\u306b\u3054\u9023\u7d61\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n

<\/div>\n\n\n\n
\n
\u3054\u76f8\u8ac7\u30d5\u30a9\u30fc\u30e0<\/a><\/div>\n<\/div>\n\n\n\n


<\/p>\n\n\n\n


\u3000\u3000<\/p>\n\n\n\n

\u3010\u53c2\u8003\u6587\u732e\u3011
\u3008Localized cancer photodynamic therapy approach based on core\u2013shell electrospun nanofibers\u3009
\u30b3\u30a2\u30b7\u30a7\u30eb\u30a8\u30ec\u30af\u30c8\u30ed\u30b9\u30d4\u30cb\u30f3\u30b0\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u306b\u57fa\u3065\u304f\u9650\u5c40\u6027\u304c\u3093\u5149\u7dda\u529b\u5b66\u7642\u6cd5\u30a2\u30d7\u30ed\u30fc\u30c1
Sofia M. Costa, Leandro M. O. Louren\u00e7o, Ricardo C. Calhelhacd, Isabel Calejo, Cristina C. Barrias, Raul Fangueiro and Diana P. Ferreira
(Centre for Textile Science and Technology (2C2T), University of Minho, 4800-058 Guimar\u00e3es, Portugal.) (https:\/\/pubs.rsc.org\/en\/content\/articlelanding\/2024\/ma\/d4ma00647j)<\/p>\n","protected":false},"excerpt":{"rendered":"

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